Biologic markers in breast carcinoma: Clinical correlations with urinary polyamines
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منابع مشابه
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متن کاملUrinary polyamines in cancer patients.
Polyamines are small hydrocarbon-amine substances which occur ubiquitously in nature (18). Because of their polycationic nature, polyamines have a strong affinity for nucleic acids in vitro, and in vivo studies indicate a possible role for these compounds in the control of rRNA metabolism (2, 4, 8—11, 13). Studies of rapid-growth systems, both normal and neoplastic, indicate that polyamine sy...
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The polyamines, spermidine and spermine, and their diamine precursor, putrescine, constitute a unidirectional biosynthetic pathway whose biosynthetic enzymes and accumulation patterns appear to play important roles in the regulation of growth processes. Concentrations of these compounds in physiological fluids are low or undetectable under normal conditions, are elevated in patients with metast...
متن کاملExpression Study and Clinical Correlations of MYC and CCAT2 in Breast Cancer Patients
Background: Colon cancer-associated transcript 2 (CCAT2) is a newly recognized lncRNA transcribed from the 8q24 genomic region. It functions as an oncogene in various types of cancers including breast cancer, in which it affects Wnt/β-catenin pathway. Previous studies have shown a putative interaction between this lncRNA and MYC proto-oncogene. Methods: In the current study, we evaluated t...
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ژورنال
عنوان ژورنال: Cancer
سال: 1980
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19800815)46:4<741::aid-cncr2820460418>3.0.co;2-7